Article
TP53 mutation in newly diagnosed acute myeloid leukemia and myelodysplastic syndrome.
Diagnostic pathology - 31 Oct 2021
Niparuck Pimjai, Police Pornnapa, Noikongdee Phichchapha, Siriputtanapong Kanchana, Limsuwanachot Nittaya, Rerkamnuaychoke Budsaba, Chuncharunee Suporn, Siriboonpiputtana Teerapong
Abstract excerpt
OBJECTIVES: TP53 mutation is found frequently in therapy related acute myeloid leukemia (AML)/ myelodysplastic syndrome (MDS), AML and MDS patients with monosomy or complex karyotype. However, the prevalence and treatment outcome in TP53 mutated AML/MDS patients in Asian population are scarce. We therefore conducted this study to analyze the prevalence and the treatment outcomes of TP53 mutation in AML and MDS-EB...
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