Article
Regulation of androgen synthesis: the late steroidogenic pathway.
Steroids - 1 Jan 1997
Dufau M L, Miyagawa Y, Takada S, Khanum A, Miyagawa H, Buczko E
Abstract excerpt
Studies of the regulation of androgen synthesis in steroidogenic cells have focused on both transcriptional and post-translational regulation of the proteins that catalyze these reactions: the P450c17 that catalyzes the production of DHEA or androstenedione in consecutive hydroxylase and lyase activities, and the 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) that catalyzes the conversion of androstenedione...
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