Article
Relative impact of HLA phenotype and CD4-CD8 ratios on the clinical expression of hemochromatosis.
Hepatology (Baltimore, Md.) - 1 Feb 1997
Porto G, Vicente C, Teixeira M A, Martins O, Cabeda J M, Lacerda R, Goncalves C, Fraga J, Macedo G, Silva B M, Alves H, Justiça B, de Sousa M
Abstract excerpt
Hemochromatosis is a hereditary iron-overload disease linked to HLA. The clinical expression of hemochromatosis is influenced by sex and age. However, other factors must account for the notorious heterogeneity of expression of the disease independent of sex, age, and HLA phenotype. The present study attempts to clarify some of these additional factors based on exhaustive statistical analysis of data collected...
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