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Article

Iron loading in HFE p.C282Y homozygotes found by population screening: relationships to HLA-type and T-lymphocyte subsets.

Scandinavian journal of clinical and laboratory investigation - 1 Nov 2017

Thorstensen Ketil, Kvitland Mona A, Irgens Wenche Ø, Åsberg Arne, Borch-Iohnsen Berit, Moen Torolf, Hveem Kristian

Abstract excerpt

Iron loading in p.C282Y homozygous HFE hemochromatosis subjects is highly variable, and it is unclear what factors cause this variability. Finding such factors could aid in predicting which patients are at highest risk and require closest follow-up. The degree of iron loading has previously been associated with certain HLA-types and with abnormally low CD8 + cell counts in peripheral blood. In 183 Norwegian,...

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Source

Identifiers

PMID: 28678636
DOI: 10.1080/00365513.2017.1342136

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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