Article
PCR-directed formation of viral hybrids in vitro.
Virology - 20 Jan 1997
Khan S A, Watson R H, Hayes S J, Serwer P
Abstract excerpt
When constructing viruses that have desired hybrid phenotypes, anticipated difficulties include the nonviability of many, possibly most, of the hybrid genomes that can be constructed by incorporation of DNA fragments. Therefore, many different hybrid genomes may have to be constructed in order to find one that is viable. To perform this combinatorial work in a single experiment, we have used bacteriophage...
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