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Article

Prenylation of oncogenic human PTP(CAAX) protein tyrosine phosphatases.

Cancer letters - 20 Dec 1996

Cates C A, Michael R L, Stayrook K R, Harvey K A, Burke Y D, Randall S K, Crowell P L, Crowell D N

Abstract excerpt

Many isoprenylated proteins are known to participate in signal transduction, but not all have been identified. Using an in vitro prenylation screen, two human cDNAs (PTP(CAAXI) and PTP(CAAX2)) homologous to the rat PRL-1 and human OV-1 protein tyrosine phosphatase genes were identified. PTP(CAAXI) and PTP(CAAX2) were farnesylated in vitro by mammalian farnesyl:protein transferase, and epitope-tagged PTP(CAAX2)...

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PMID: 9018080
DOI: 10.1016/s0304-3835(96)04459-x

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PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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