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Article

Breast cancer cell targeting by prenylation inhibitors elucidated in living animals with a bioluminescence reporter.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2012

Chinault Sharon L, Prior Julie L, Kaltenbronn Kevin M, Penly Anya, Weilbaecher Katherine N, Piwnica-Worms David, Blumer Kendall J

Abstract excerpt

PURPOSE: Inhibitors of protein prenylation, including prenyltransferase inhibitors and aminobisphosphonates such as zoledronic acid, are being investigated intensively as therapeutics in cancer and other diseases. Determining whether prenylation inhibitors directly or indirectly target tumor and/...

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Identifiers

PMID: 22693355
DOI: 10.1158/1078-0432.CCR-12-0642
PMCID: PMC3605717

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22693355-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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