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Article

Deletion polymorphism of angiotensin-converting enzyme gene and left ventricular hypertrophy in southern Italian patients.

Journal of the American College of Cardiology - 1 Feb 1997

Perticone F, Ceravolo R, Cosco C, Trapasso M, Zingone A, Malatesta P, Perrotti N, Tramontano D, Mattioli P L

Abstract excerpt

OBJECTIVES: This study sought to evaluate the possible association of polymorphism of the angiotensin-converting enzyme (ACE) gene with blood pressure and left ventricular mass index (LVMI). BACKGROUND: The renin-angiotensin system seems to be involved in the pathogenesis of essential hypertension. Moreover, recent epidemiologic observations demonstrate that many subjects with left ventricular hypertrophy have...

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Source

Identifiers

PMID: 9014990
DOI: 10.1016/s0735-1097(96)00485-8

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletion polymorphism of angiotensin-converting enzyme gene and left ventricular hypertrophy in southern Italian patients.PMID 9014990Read ↗

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The relationship between blood pressure and left ventricular mass in essential hypertension is observed only in the presence of the angiotensin-converting enzyme gene deletion allele.Semantic proximity Read ↗

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