Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension.

doi:10.1016/s0002-9149(96)00198-1

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Article

Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension.

The American journal of cardiology - 15 Jun 1996

Gharavi A G, Lipkowitz M S, Diamond J A, Jhang J S, Phillips R A

Abstract excerpt

An insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene is associated with myocardial infarction, cardiomyopathy, and left ventricular (LV) hypertrophy. LV mass and geometry are related to cardiovascular morbidity and mortality. Two-dimensional directed M-mode ech...

Topics

Adult
Blood Pressure Monitoring, Ambulatory
Case-Control Studies
Echocardiography
Female
Gene Deletion
Genotype
Humans
Hypertension
Hypertrophy, Left Ventricular
Linear Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Peptidyl-Dipeptidase A

Polymerase Chain Reaction

Polymorphism, Genetic

Renin-Angiotensin System

Source

Open in PubMed

Identifiers

PMID: 8677872
DOI: 10.1016/s0002-9149(96)00198-1

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8677872-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Deletion polymorphism of the angiotensin-converting enzyme gene is independently associated with left ventricular mass and geometric remodeling in systemic hypertension.PMID 8677872Read ↗

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