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Article

Transcriptional regulation of human CYP11A1 in gonads and adrenals.

Journal of biomedical science - 1 Jul 2007

Guo Ing-Cherng, Shih Meng-Chun, Lan Hsin-Chieh, Hsu Nai-Chi, Hu Meng-Chun, Chung Bon-Chu

Abstract excerpt

The CYP11A1 gene encodes the cholesterol side-chain cleavage enzyme, also termed cytochrome P450scc, which catalyzes the conversion of cholesterol to pregnenolone in the first step of steroid biosynthesis in mitochondria. The adrenal- and gonad-selective, hormonally and developmentally regulated expression of CYP11A1 is principally driven by its 2.3 kb promoter. Multiple trans-acting factors like SF-1, Sp1, AP-2,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17594537
DOI: 10.1007/s11373-007-9177-z

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LBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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