Pathogenesis of chronic liver disease in patients with chronic hepatitis B virus infection without serum HBeAg.

doi:10.1007/BF02100141

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Article

Pathogenesis of chronic liver disease in patients with chronic hepatitis B virus infection without serum HBeAg.

Digestive diseases and sciences - 1 Dec 1996

Mangia A, Chung Y H, Hoofnagle J H, Birkenmeyer L, Mushahwar I, Di Bisceglie A M

Abstract excerpt

Chronic hepatitis B in patients lacking hepatitis B e antigen has been attributed to a hepatitis B virus variant (G-to-A mutation at nucleotide 1896 in the precore region of the genome). We therefore assessed the frequency and significance of this variant among 43 United States patients (10 with...

Topics

Adult
Asian
Base Sequence
Carrier State
Chronic Disease
Cohort Studies
DNA, Viral
Female
Genotype
Hepatitis B
Hepatitis B Antigens
Hepatitis B virus
Humans
Immunoglobulin M
Incidence
Male
Middle Aged
Serologic Tests

Source

Open in PubMed

Identifiers

PMID: 9011456
DOI: 10.1007/BF02100141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9011456-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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