Article
Detection and significance of a G1862T variant of hepatitis B virus in Chinese patients with fulminant hepatitis.
The Journal of general virology - 1 Sept 2002
Hou Jinlin, Lin Yulong, Waters Jenny, Wang Zhanhui, Min Jia, Liao Huiyu, Jiang Jiaji, Chen Jinjun, Luo Kangxian, Karayiannis Peter
Abstract excerpt
The prevalence of a G1862T variant of hepatitis B virus (HBV) has been investigated in patients with fulminant hepatitis and chronic liver disease, using primer mismatch amplification, followed by restriction fragment length polymorphism analysis. This variant was five times more common in patients with fulminant hepatitis (13.7%, 7 of 52) than in chronic carriers (2.5%, 2 of 81). The G-->T substitution at...
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