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Article

Evaluation of a live-attenuated foot-and-mouth disease virus as a vaccine candidate.

Virology - 6 Jan 1997

Mason P W, Piccone M E, Mckenna T S, Chinsangaram J, Grubman M J

Abstract excerpt

A variant of foot-and-mouth disease virus (FMDV) lacking the leader (L) coding region (A12-LLV2) was previously constructed and shown to be less virulent in cattle than its wild-type parent (A12-IC). In this study, cattle were tested for their clinical and immunological responses to subcutaneous inoculation with A12-LLV2 or A12-IC or to intramuscular vaccination with chemically inactivated A12-IC. Five weeks...

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Source

Identifiers

PMID: 9007062
DOI: 10.1006/viro.1996.8309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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