Article
Novel BVDV-2 mutants as new candidates for modified-live vaccines.
Veterinary microbiology - 21 Apr 2010
Zemke Johanna, König Patricia, Mischkale Katrin, Reimann Ilona, Beer Martin
Abstract excerpt
Protection against Bovine viral diarrhea virus (BVDV) type 2 infection of commercially available vaccines is often limited due to marked genetic and antigenic differences between BVDV types 1 (BVDV-1) and 2 (BVDV-2). Therefore, the immunogenicity of selected BVDV-1 and BVDV-2 mutants derived from infectious full-length cDNA clones and their use as modified-live vaccine candidates against challenge infection with...
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