Article
Internal deletions in the yeast transcriptional activator HAP1 have opposite effects at two sequence elements.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 1990
Kim K S, Pfeifer K, Powell L, Guarente L
Abstract excerpt
In this report we study the effects of internal deletions of the yeast transcriptional activator HAP1 (CYP1) on activity at two dissimilar DNA binding sites, upstream activation sequence 1 (UAS1) of CYC1 (iso-1-cytochrome c) and CYC7 (iso-2-cytochrome c). These deletions remove up to 1061 amino a...
Topics
- Chromosome Deletion
- Cytochrome c Group
- Cytochromes c
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Metalloproteins
- Mutation
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Trans-Activators
- Transcription Factors