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Article

Rearrangement and reactivation of the myelin basic protein locus in myelin-deficient (mld) mouse brain.

Journal of neurochemistry - 1 Feb 1997

Sun Y, Xu J, Barbarese E, Carson J H

Abstract excerpt

Myelin-deficient (mld) is a complex mutation affecting the myelin basic protein (MBP) locus of the mouse. It consists of duplication and partial inversion of the MBP gene and results in a dysfunctional MBP locus. The mutant phenotype is reversed, both in vivo and in vitro, in approximately 5% of mld oligodendrocytes. One possible mechanism for the somatic reversion is recombination between homologous sequences of...

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Source

Identifiers

PMID: 9003030
DOI: 10.1046/j.1471-4159.1997.68020457.x

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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