Article
Molecular biology of myelin basic protein: gene rearrangement and expression of anti-sense RNA in myelin-deficient mutants.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology - 1 Jan 1991
Mikoshiba K, Aruga J, Okano H
Abstract excerpt
1. Myelin is an important structure for facilitating the conduction of impulses along the axons both in the central nervous system (CNS) and peripheral nervous system (PNS). 2. Myelin basic protein (MBP) is a major protein in CNS myelin. 3. MBP is expressed specifically in the nervous system. 4. The MBP gene has been cloned and characterized. 5. Two mutant mice, Shiverer (shi) and myelin-deficient (mld. shimid),...
Topics
- Animals
- Base Sequence
- Gene Expression Regulation
- Gene Rearrangement
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data
- Mutation
- Myelin Basic Protein
- RNA, Antisense