Article
Injured primary sensory neurons switch phenotype for brain-derived neurotrophic factor in the rat.
Neuroscience - 1 Jan 1999
Zhou X F, Chie E T, Deng Y S, Zhong J H, Xue Q, Rush R A, Xian C J
Abstract excerpt
Peripheral nerve injury results in plastic changes in the dorsal root ganglia and spinal cord, and is often complicated with neuropathic pain. The mechanisms underlying these changes are not known. We have now investigated the expression of brain-derived neurotrophic factor in the dorsal root ganglia with histochemical and biochemical methods following sciatic nerve lesion in the rat. The percentage of neurons...
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