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[Overcoming the "2-cell block" in mouse embryos in aggregation chimeras].

Ontogenez - 1 Jan 2000

Sekirina G G, Neganova I E

Abstract excerpt

The embryos of the inbred mouse strain BALB/c are predisposed to so-called "two-cell block" after explantation from the maternal organism before the late two-cell stage and cultivation in a standard synthetic medium. Hybrid embryos (CBA x C57B1) F2 are competent to complete preimplantation development in vitro. The BALB/c embryo predisposed to block ("blocking") at the early two-cell stage was aggregated using...

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PMID: 8999390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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