Article
Analysis of specific factors generating 2-cell block in AKR mouse embryos.
Zygote (Cambridge, England) - 1 May 2006
Yoneda Akihiro, Okada Aki, Wakayama Teruhiko, Ueda Junji, Watanabe Tomomasa
Abstract excerpt
The phenomenon of the developmental arrest at the 2-cell stage of 1-cell embryos from some mouse strains during in vitro culture is known as the 2-cell block. We investigated the specific factors involved in the 2-cell block of AKR embryos by means of a modified culture system, the production of reconstructed embryos by pronuclear exchange and a cross experiment. In a culture medium with phosphate, 94.6% of...
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