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Article

[Expression of mutant genes in mouse aggregation chimeras. 4. The aphakia gene].

Ontogenez - 1 Jan 2000

Koniukhov B V, Kupriianov S D

Abstract excerpt

Analysis of aphakia (ak) gene expression in ak/ak C/C in equilibrium +/+ c/c experimental chimaeras has shown that the ak gene acts in the lens rudiment cells blocking it differentiation. In the lens of 12 day old ak/ak C/C in equilibrium +/+ c/c chimaeric embryos undifferentiated ak/ak cells were present among the normally differentiating fibres. In 14 and 18 day old chimaeric embryos and 20 day old chimaeric...

Topics

Animals
Aphakia
Cell Differentiation
Cell Division
Chimera
Culture Techniques
Gene Expression Regulation
Genes, Recessive
Genotype
Lens, Crystalline
Mice
Mutation

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Identifiers

PMID: 4047586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-4047586-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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