Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene.

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Article

Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene.

Investigative ophthalmology & visual science - 1 Apr 1997

Savontaus M, Ihanamäki T, Metsäranta M, Vuorio E, Sandberg-Lall M

Abstract excerpt

PURPOSE: To elucidate the function of type II collagen in the development and diseases of the eye by analyzing the temporospatial expression of the long (IIA) and short (IIB) isoforms of type II collagen in the normal and transgenic Dell mice. METHODS: Normal and Dell transgenic embryos harboring...

Topics

Abnormalities, Multiple
Animals
Blotting, Northern
Collagen
Eye
Eye Abnormalities
Female
Gene Deletion
In Situ Hybridization
Male
Mice
Mice, Transgenic
Mutation
Procollagen
RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 9112989

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9112989-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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