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Article

The ICP22 protein of equine herpesvirus 1 cooperates with the IE protein to regulate viral gene expression.

Journal of virology - 1 Feb 1997

Kim S K, Holden V R, O'Callaghan D J

Abstract excerpt

The equine herpesvirus 1 (EHV-1) immediate-early (IE) phosphoprotein is essential for the activation of transcription from viral early and late promoters and regulates transcription from its own promoter. The EHV-1 EICP22 protein, a homolog of ICP22 of herpes simplex virus, increased the in vitro DNA binding activity of the IE protein for sequences in the IE, early, and late promoters. The EICP22 protein affected...

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Share to Gene Expression Regulation, Viral
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Transcription, Genetic

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Source

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Identifiers

PMID: 8995619
DOI: 10.1128/JVI.71.2.1004-1012.1997
PMCID: PMC191150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The ICP22 protein of equine herpesvirus 1 cooperates with the IE protein to regulate viral gene expression.PMID 8995619Read ↗

Characterization of DNA binding properties of the immediate-early gene product of equine herpesvirus type 1.Semantic proximity Read ↗

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Identification of functional domains of the IR2 protein of equine herpesvirus 1 required for inhibition of viral gene expression and replication.Semantic proximity Read ↗

Initial characterization of 17 viruses harboring mutant forms of the immediate-early gene of equine herpesvirus 1.Semantic proximity Read ↗

Identification of the Promoter Antisense Transcript Enhancing the Transcription of the Equine Herpesvirus 1 Immediate Early GeneSemantic proximity Read ↗

Complementation of a replication-defective mutant of equine herpesvirus type 1 by a cell line expressing the immediate-early protein.Semantic proximity Read ↗

Identification of sequences in herpes simplex virus type 1 ICP22 that influence RNA polymerase II modification and viral late gene expression.Semantic proximity Read ↗

Equine herpesvirus type 1 tegument protein VP22 is not essential for pathogenicity in a hamster model, but is required for efficient viral growth in cultured cells.Semantic proximity Read ↗

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Biological and genotypic properties of defective interfering particles of equine herpesvirus 1 that mediate persistent infection.Semantic proximity Read ↗

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Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression.Semantic proximity Read ↗

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