Article

Identification of the Promoter Antisense Transcript Enhancing the Transcription of the Equine Herpesvirus 1 Immediate Early Gene

2024-05-14

Abstract excerpt

Equine herpesvirus-1 (EHV-1) causes respiratory diseases, abortion, and encephalomyelitis in horses. EHV-1 immediate-early (IE) protein, essential for viral replication, is transactivated by the binding of a multiprotein complex including the open reading frame 12 (ORF12) and some host factors to the IE promoter region. Promoter-associated non-coding RNAs (pancRNAs), which are transcribed from bidirectional promot...

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Literature Corpus work: 26d92d7a-ea6d-5576-9900-11237d60a9dd
DOI: 10.20944/preprints202405.0974.v1

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