Article
Complementation of a replication-defective mutant of equine herpesvirus type 1 by a cell line expressing the immediate-early protein.
Virology - 15 Aug 1998
Garko-Buczynski K A, Smith R H, Kim S K, O'Callaghan D J
Abstract excerpt
Equine herpesvirus type 1 (EHV-1) possesses a sole, diploid immediate-early (IE) gene that encodes a major regulatory protein of 1487 amino acids capable of modulating expression of both early and late EHV-1 promoters and capable of trans-repressing its own promoter. In this study, a rabbit kidne...
Topics
- Animals
- Cell Line
- Cell Nucleus
- DNA Replication
- Fluorescent Antibody Technique, Indirect
- Genes, Immediate-Early
- Genetic Complementation Test
- Herpesvirus 1, Equid
- Horses
- Immediate-Early Proteins
- Kidney
- Kinetics
- L Cells
- Mice
- Mutation
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Rabbits