Article
Biological and genotypic properties of defective interfering particles of equine herpesvirus 1 that mediate persistent infection.
Virology - 10 Nov 2008
Ebner Paul D, Kim Seong K, O'Callaghan Dennis J
Abstract excerpt
Infection with equine herpesvirus 1 (EHV-1) preparations enriched for defective interfering particles (DIP) leads to a state of persistent infection in which infected cells become lysis resistant and release both infectious (standard) virus and DIP. EHV-1 DIP are unique in that the recombination events that generate DIP genomes produce new open reading frames (ORFs; Hyb1.0 and Hyb2.0) consisting of 5' sequences...
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