Article
Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins.
Journal of virology - 1 Apr 1990
Malone C L, Vesole D H, Stinski M F
Abstract excerpt
Expression from a human cytomegalovirus early promoter (E1.7) has been shown to be activated in trans by the IE2 gene products (C.-P. Chang, C. L. Malone, and M. F. Stinski, J. Virol. 63:281-290, 1989). Using wild-type and mutant viral proteins, we have defined the protein regions required for tr...
Topics
- Amino Acid Sequence
- Cytomegalovirus
- Humans
- Immediate-Early Proteins
- Membrane Glycoproteins
- Molecular Sequence Data
- Mutation
- Plasmids
- Precipitin Tests
- Promoter Regions, Genetic
- RNA, Messenger
- RNA, Viral
- Restriction Mapping
- Trans-Activators
- Transcriptional Activation
- Transfection
- Viral Envelope Proteins
- Viral Proteins