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Article

CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1.

Journal of virology - 1 Feb 1997

Kozak S L, Platt E J, Madani N, Ferro F E, Peden K, Kabat D

Abstract excerpt

We have used a focal infectivity method to quantitatively analyze the CD4, CXCR-4, and CCR-5 dependencies for infections by diverse primary patient (PR) and laboratory-adapted (LA) isolates of human immunodeficiency virus type 1 (HIV-1). Infectivities of T-cell-tropic viruses were analyzed in a p...

Topics

Acquired Immunodeficiency Syndrome
CD4 Antigens
HIV Envelope Protein gp120
HIV-1
HeLa Cells
Humans
Membrane Proteins
Mutation
Receptors, CCR5
Receptors, CXCR4
Receptors, Cytokine
Receptors, HIV

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

T-Lymphocyte Subsets

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Identifiers

PMID: 8995603
DOI: 10.1128/JVI.71.2.873-882.1997
PMCID: PMC191134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8995603-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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