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Article

A broad range of chemokine receptors are used by primary isolates of human immunodeficiency virus type 2 as coreceptors with CD4.

Journal of virology - 1 May 1998

McKnight A, Dittmar M T, Moniz-Periera J, Ariyoshi K, Reeves J D, Hibbitts S, Whitby D, Aarons E, Proudfoot A E, Whittle H, Clapham P R

Abstract excerpt

Like human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV), HIV-2 requires a coreceptor in addition to CD4 for entry into cells. HIV and SIV coreceptor molecules belong to a family of seven-transmembrane-domain G-protein-coupled receptors. Here we show that primary HIV-2 isolates can use a broad range of coreceptor molecules, including CCR1, CCR2b, CCR3, CCR4, CCR5, and CXCR4....

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Share to CD4 Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukocytes, Mononuclear

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Source

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Identifiers

PMID: 9557695
DOI: 10.1128/JVI.72.5.4065-4071.1998
PMCID: PMC109635

Genes

CXCR4
CCR1
CCR3
CCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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