Article
Sequence requirements for regulated RNA splicing of the human fibroblast growth factor receptor-1 alpha exon.
The Journal of biological chemistry - 10 Jan 1997
Cote G J, Huang E S, Jin W, Morrison R S
Abstract excerpt
Progression of astrocytes from a benign to a malignant phenotype is accompanied by a change in the RNA processing of the fibroblast growth factor receptor 1 (FGFR-1) gene. The level of a high affinity form of the FGFR-1 is dramatically elevated as a result of alpha-exon skipping during RNA splici...
Topics
- Base Sequence
- Exons
- Humans
- Introns
- Molecular Sequence Data
- Phenotype
- RNA Splicing
- Receptor Protein-Tyrosine Kinases
- Receptor, Fibroblast Growth Factor, Type 1
- Receptors, Fibroblast Growth Factor
- Sequence Deletion
