Article
Sequence analysis of the V1-V2 hypervariable region of the HIV-1 envelope gene from pediatric patients.
Puerto Rico health sciences journal - 1 Sept 1996
Ramos Martinez S L, Mendez I, Delgado R, Cadilla C L
Abstract excerpt
The presence of HIV-1 DNA sequence variants of pediatric AIDS patients was investigated in a two-stage polymerase chain reaction (PCR) using nested primers for the first and second (V1-V2) hypervariable regions of the proviral envelope (gp 120) gene (env1). Gel electrophoresis analysis yielded am...
Topics
- Amino Acid Sequence
- Base Sequence
- Child
- Child, Preschool
- DNA, Viral
- Genetic Variation
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Humans
- Immunoglobulin Variable Region
- Infant
- Infectious Disease Transmission, Vertical
- Molecular Sequence Data
- Molecular Weight
- Polymerase Chain Reaction
- Puerto Rico
- Sequence Analysis, DNA