Article
Selection of appropriate HIV-1 genomic regions for single-strand conformation polymorphism analysis of the diversity, modification, and transmission of HIV-1 quasispecies.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 15 Aug 1998
Lin H J, Siwak E B, Lauder I J, Hollinger F B
Abstract excerpt
Single-strand conformation polymorphism (SSCP) analysis is a useful tool for studying viral quasispecies. Four regions within the HIV-1 genome were studied by means of SSCP analysis with the aim of determining which regions were the most informative for the study of HIV-1 transmission or for detection of changes in HIV-1 quasispecies populations. Nested polymerase chain reaction (PCR) was used to amplify V1, V2,...
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