Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1.

doi:10.1128/JVI.69.6.3778-3788.1995

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Article

Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1.

Journal of virology - 1 Jun 1995

Briant L, Wade C M, Puel J, Brown A J, Guyader M

Abstract excerpt

In order to elucidate the molecular mechanisms involved in human immunodeficiency virus type 1 (HIV-1) mother-to-child transmission, we have analyzed the genetic variation within the V3 hypervariable domain and flanking regions of the HIV-1 envelope gene in four mother-child transmission pairs. Phylogenetic analysis and amino acid sequence comparison were performed on cell-associated viral sequences derived from...

Topics

Adult
Amino Acid Sequence
Base Sequence
DNA Primers
Female
Gene Products, env
Genetic Heterogeneity
Glycosylation
HIV Infections
HIV-1
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant, Newborn

Infectious Disease Transmission, Vertical

Molecular Sequence Data

Mutation

Phenotype

Phylogeny

Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 7745725
DOI: 10.1128/JVI.69.6.3778-3788.1995
PMCID: PMC189095

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7745725-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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