Sequence diversity of V1 and V2 domains of gp120 from human immunodeficiency virus type 1: lack of correlation with viral phenotype.

doi:10.1128/JVI.69.4.2708-2715.1995

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Article

Sequence diversity of V1 and V2 domains of gp120 from human immunodeficiency virus type 1: lack of correlation with viral phenotype.

Journal of virology - 1 Apr 1995

Wang N, Zhu T, Ho D D

Abstract excerpt

We analyzed by PCR and direct sequencing 57 viral sequences from 47 individuals infected with human immunodeficiency virus type 1, focussing on the V1 and V2 regions of gp120. There was extensive length polymorphism in the V1 region, which rendered sequence alignment difficult. The V2 hypervariab...

Topics

Amino Acid Sequence
Base Sequence
Cells, Cultured
Consensus Sequence
DNA Primers
Genetic Variation
HIV Envelope Protein gp120
HIV-1
Humans
Molecular Sequence Data
Phenotype
Phylogeny
Sequence Homology, Amino Acid

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