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Article

Independent variation and positive selection in env V1 and V2 domains within maternal-infant strains of human immunodeficiency virus type 1 in vivo.

Journal of virology - 1 Jul 1993

Lamers S L, Sleasman J W, She J X, Barrie K A, Pomeroy S M, Barrett D J, Goodenow M M

Abstract excerpt

Multiple targets for immune recognition and cellular tropism are localized to the V1 and V2 hypervariable regions in the amino portion of human immunodeficiency virus type 1 (HIV-1) gp120env. We have assessed genetic diversity in env V1 and V2 hypervariable domains in vivo within epidemiologicall...

Topics

Amino Acid Sequence
Base Sequence
Female
Genes, env
Genetic Variation
HIV Infections
HIV-1
Humans
Infant
Infant, Newborn
Male
Maternal-Fetal Exchange

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Oligodeoxyribonucleotides

Pregnancy

Sequence Alignment

Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 8510212
DOI: 10.1128/JVI.67.7.3951-3960.1993
PMCID: PMC237762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8510212-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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