Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1.

doi:10.1128/JVI.64.12.5840-5850.1990

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Article

Analysis of sequence diversity in hypervariable regions of the external glycoprotein of human immunodeficiency virus type 1.

Journal of virology - 1 Dec 1990

Simmonds P, Balfe P, Ludlam C A, Bishop J O, Brown A J

Abstract excerpt

Nucleotide sequences in three hypervariable regions of the human immunodeficiency virus type 1 (HIV-1) env gene were obtained by sequencing provirus present in peripheral blood mononuclear cells of HIV-infected individuals. Single molecules of target sequences were isolated by limiting dilution a...

Topics

Amino Acid Sequence
Base Sequence
DNA, Viral
Genetic Variation
HIV Envelope Protein gp120
HIV Seropositivity
HIV-1
Hemophilia A
Humans
Molecular Sequence Data
Molecular Weight
Oligonucleotide Probes
Phylogeny
Polymerase Chain Reaction
Proviruses
Sequence Homology, Nucleic Acid

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Identifiers

PMID: 2243378
DOI: 10.1128/JVI.64.12.5840-5850.1990
PMCID: PMC248744

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2243378-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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