Article
Cytotoxic T cell immunity to human cytomegalovirus glycoprotein B.
Journal of medical virology - 1 Jun 1996
Hopkins J I, Fiander A N, Evans A S, Delchambre M, Gheysen D, Borysiewicz L K
Abstract excerpt
Human cytomegalovirus (HCMV) is associated with significant morbidity and mortality following immunosuppression and in pregnancy. HCMV infection may be accompanied by acute disease but persists asymptomatically. Cytotoxic T lymphocytes (CTL) appear to be an important immune effector mechanism in maintaining the normal host-virus equilibrium. Glycoprotein B may be an important target for future subunit vaccines as...
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