Article

HCMV glycoprotein B subunit vaccine efficacy was mediated by non-neutralizing antibody effector functions

2018-01-11

Abstract excerpt

Human cytomegalovirus (HCMV) is the most common congenital infection worldwide, frequently causing hearing loss and brain damage in afflicted infants. A vaccine to prevent maternal acquisition of HCMV during pregnancy is necessary to reduce the incidence of infant disease. The glycoprotein B (gB) + MF59 adjuvant subunit vaccine platform is the most successful HCMV vaccine tested to-date, demonstrating approximatel...

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Literature Corpus work: 5a7c8c5d-ac0e-5fa1-a313-8a322ea1dc3b
DOI: 10.1101/246884

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