Article
Limited Effector Memory B-Cell Response to Envelope Glycoprotein B During Primary Human Cytomegalovirus Infection.
The Journal of infectious diseases - 15 May 2016
Dauby Nicolas, Sartori Delphine, Kummert Caroline, Lecomte Sandra, Haelterman Edwige, Delforge Marie-Luce, Donner Catherine, Mach Michael, Marchant Arnaud
Abstract excerpt
BACKGROUND: Following primary human cytomegalovirus (HCMV) infection, the production of antibodies against envelope glycoprotein B (gB) is delayed, compared with production of antibodies against tegument proteins, and this likely reduces the control of HCMV dissemination. METHODS: The frequency and the phenotype of gB-specific and tegument protein-specific B cells were studied in a cohort of pregnant women with...
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