Article
Detection of Genotype-Specific Antibody Responses to Glycoproteins B and H in Primary and Non-Primary Human Cytomegalovirus Infections by Peptide-Based ELISA.
Viruses - 3 Mar 2021
Zavaglio Federica, Fiorina Loretta, Suárez Nicolás M, Fornara Chiara, De Cicco Marica, Cirasola Daniela, Davison Andrew J, Gerna Giuseppe, Lilleri Daniele
Abstract excerpt
BACKGROUND: Strain-specific antibodies to human cytomegalovirus (HCMV) glycoproteins B and H (gB and gH) have been proposed as a potential diagnostic tool for identifying reinfection. We investigated genotype-specific IgG antibody responses in parallel with defining the gB and gH genotypes of the infecting viral strains. METHODS: Subjects with primary (n = 20) or non-primary (n = 25) HCMV infection were studied....
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