Article
Characterization of mutant HA-ras gene expression in transformed murine keratinocyte lines grown under in vitro and in vivo conditions.
Molecular carcinogenesis - 1 Dec 1996
Volpe J P, Conti C J, Slaga T J
Abstract excerpt
We investigated the Ha-ras and Ki-ras gene status, tumorigenicity, pathology, line derivation, and intercellular communication of 7,12-dimethylbenz[a]anthracene-initiated papilloma-, carcinoma-, and hyperplastic skin-producing cell lines to further characterize them. Six of nine tumor cell lines...
Topics
- 9,10-Dimethyl-1,2-benzanthracene
- Animals
- Carcinogens
- Carcinoma, Squamous Cell
- Cell Communication
- Cell Division
- Cell Line, Transformed
- Gene Expression
- Genes, ras
- Keratinocytes
- Mice
- Mice, Nude
- Mutation
- Papilloma
- Skin Neoplasms
- Tumor Cells, Cultured