Article
A sorting motif localizes the foamy virus glycoprotein to the endoplasmic reticulum.
Journal of virology - 1 Jan 1997
Goepfert P A, Shaw K L, Ritter G D, Mulligan M J
Abstract excerpt
We recently identified an endoplasmic reticulum (ER) retrieval signal-the dilysine motif-in the glycoproteins of all five foamy viruses (FVs) for which sequences were available (P. A. Goepfert, G. Wang, and M. J. Mulligan, Cell 82:543-544, 1995). In the present study, expression of recombinant human FV (HFV) glycoprotein and analyses of oligosaccharide modifications and precursor cleavage indicated that the...
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