Article
Determinants of foamy virus envelope glycoprotein mediated resistance to superinfection.
Virology - 15 Sept 2003
Berg Angelika, Pietschmann Thomas, Rethwilm Axel, Lindemann Dirk
Abstract excerpt
Little is known about the nature of foamy virus (FV) receptor molecules on target cells and their interaction with the viral glycoproteins. Similar to other viruses, cellular expression of the FV Env protein is sufficient to induce resistance to exogenous FV, a phenomenon called superinfection resistance (SIR). In this study we define determinants of the FV Env protein essential for mediating SIR. FV Env requires...
Topics
- Animals
- Cats
- Cattle
- Cell Line
- Cell Membrane
- Gene Products, env
- Humans
- Leukemia Virus, Murine
- Membrane Fusion
- Mutation
- Receptors, Virus
- Spumavirus
- Transduction, Genetic
- Vesicular stomatitis Indiana virus
