Article
B-CLL cells with unusual properties.
International journal of cancer - 6 Jan 1997
Avila-Cariño J, Lewin N, Tomita Y, Szeles A, Sandlund A, Mosolits S, Mellstedt H, Klein G, Klein E
Abstract excerpt
In studies concerning the interaction of B-CLL cells and Epstein-Barr virus (EBV), we encountered one patient whose cells had several unusual properties. In addition to the B-cell markers, the CLL cells expressed the exclusive T-cell markers CD3 and CD8 and carried a translocation t(18,22)(q21;q1...
Topics
- Aged
- Antigens, CD
- Biomarkers, Tumor
- Cell Survival
- Cell Transformation, Viral
- Chromosomes, Human, Pair 18
- Chromosomes, Human, Pair 22
- Herpesvirus 4, Human
- Humans
- Immunophenotyping
- Leukemia, Lymphocytic, Chronic, B-Cell
- Male
- Phenotype
- T-Lymphocytes
- T-Lymphocytes, Cytotoxic
- Translocation, Genetic
- Tumor Cells, Cultured
- Tumor Virus Infections
