Article
A new Ph1+, bcr cell line derived from a patient with ALL-L1 gained autonomy in culture concomitant to CD23 expression.
Leukemia - 1 May 1990
Grausz D, Lanotte M, Valensi F, Hillion J, Chen S J, Chen Z, Morinet F, Berger R
Abstract excerpt
A permanent cell line, LEF1, has been established from the cells of an adult suffering from a Philadelphia positive acute lymphoblastic leukemia. The LEF1 cell line was obtained by maintaining peripheral blood cells from the patient in culture on a fibroblast feeder; subsequently, an autonomously growing cell population, independent of that feeder layer, developed. The karyotype of the cell line, 46,...
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