Article
Correlation between P450 CYP1A1 inducibility, MspI genotype and lung cancer incidence.
European journal of cancer (Oxford, England : 1990) - 1 Sept 1996
Jacquet M, Lambert V, Baudoux E, Muller M, Kremers P, Gielen J
Abstract excerpt
The aim of this study was to verify a possible correlation between CYP1A1 induction, MspI genotype and lung cancer incidence. A case-control study was performed on 48 lung cancer patients and 81 healthy subjects to test the existence of a correlation, within a European population. The hyperinducible group exhibited a significantly higher risk of lung cancer (odds ratio = 3.41; P = 0.036), especially for...
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