Article
CD45 molecule in gammadelta T-cell generation: disruption of CD45 exon 6 does not affect Vgamma3 dendritic epidermal T-cell development.
The Journal of investigative dermatology - 1 Jan 1997
Wang B, Fujisawa H, Kondo S, Shivji G G, Sauder D N
Abstract excerpt
There are two distinct lineages of T cells: T-cell receptor (TCR) alphabeta-bearing cells (alphabeta T cells) and TCR gammadelta-bearing cells (gammadelta T cells). All of the alphabeta T cells and most subsets of gammadelta T cells develop in the thymus. It has been demonstrated that the protein...
Topics
- Animals
- Cell Count
- Cell Division
- Dendritic Cells
- Epidermal Cells
- Exons
- Flow Cytometry
- Immunophenotyping
- Leukocyte Common Antigens
- Lymph Nodes
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Phenotype
- Polymerase Chain Reaction
- Receptors, Antigen, T-Cell, gamma-delta
- T-Lymphocytes
- Th1 Cells