Article
Requirement of the IL-2 receptor beta chain for the development of Vgamma3 dendritic epidermal T cells.
The Journal of investigative dermatology - 1 Jun 1998
Kawai K, Suzuki H, Tomiyama K, Minagawa M, Mak T W, Ohashi P S
Abstract excerpt
Vgamma3 TCR cells develop in the fetal thymus and migrate to the skin as dendritic epidermal T cells (DETC). Fetal Vgamma3 thymocytes differentiate from immature heat stable antigen (HSA)high cells to mature HSAlow cells and the latter subset predominantly expresses IL-2 receptor beta chain (IL-2...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Cell Division
- Dendritic Cells
- Epidermal Cells
- Epidermis
- Fetus
- Immunoglobulin Variable Region
- Interleukin-2
- Interleukin-5
- Lymphocyte Count
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Organ Culture Techniques
- RNA, Messenger
- Receptors, Antigen, T-Cell, gamma-delta