Article
Allelotype profiles of local recurrences and distant metastases from colorectal-cancer patients.
International journal of cancer - 20 Dec 1996
Thorstensen L, Qvist H, Nesland J M, Giercksky K E, Lothe R A
Abstract excerpt
Several genetic alterations have been described in benign and malignant primary tumors of the colorectum, but few such associations have been made with the progression of these tumors. This study compares genetic changes found in distant metastases (n = 22) with local recurrences (n = 15) as well as with primary carcinomas (n = 12). Complete allelotypes of the tumors were obtained by analyzing 43 microsatellite...
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