Article
DRD2 dopamine receptor genotype, linkage disequilibrium, and alcoholism in American Indians and other populations.
Alcoholism, clinical and experimental research - 1 Apr 1993
Goldman D, Brown G L, Albaugh B, Robin R, Goodson S, Trunzo M, Akhtar L, Lucas-Derse S, Long J, Linnoila M
Abstract excerpt
We defined interpopulation differences in the frequency of the dopamine D2 receptor DRD2/Taq1 A1 allele, which has previously been associated with alcoholism. Frequencies of the A1 allele in unrelated subjects were 0.18 to 0.20 (se = 0.02 to 0.03) in several Caucasian populations previously asses...
Topics
- Adult
- Alcoholism
- Alleles
- Black People
- Gene Frequency
- Genetic Markers
- Genotype
- Humans
- Indians, North American
- Linkage Disequilibrium
- Models, Genetic
- Receptors, Dopamine D2